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Description
When meals are consumed too close to bedtime, eaten sporadically, or spaced too far apart, this rhythm is disrupted

Most proposed mechanisms at the molecular level have only been observed in cell systems or animal models, but not confirmed in humans

(4) S.Seiwerth et al (2018) BPC 157 and Standard Angiogenic Growth Factors

Animals were housed either individually (social isolation group) or in groups of 3-4 per cage (group-housed controls) under standardized laboratory conditions: 12-h light/dark cycle (lights on at 06:00), ambient temperature maintained at 20 C22 C, and relative humidity of 55%60%

Drug Metab Dispos 2008;36(7):13751384
