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The global shortage of novel antibiotics represents a significant research gap that threatens modern medicine in the face of escalating antibacterial resistance and the antibiotic development pipeline remains alarmingly sparse

However, it reduces cellular uptake and endosomal escape, leading to lower delivery efficiency

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Folic acid is essential for cell maturation, and its deficiency causes several conditions

1.1 Biological Sources of L-Ergothioneine The synthesis of LMW thiol compounds is widespread in prokaryotic and eukaryotic organisms ( Actinomycetales ( Mycobacteria ( Cyanobacteria ( Neuropora crassa ( Pleurotus genus (including P