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As signaling molecules, bile acids can influence the gut microbiota, epithelial barrier integrity, and intestinal immune responses by activating various bile acid receptors, such as the farnesoid X receptor (FXR), vitamin D receptor, and the G protein-coupled bile acid receptor 1 (42)

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J Cosmet Dermatol

Children receiving CRWP showed a significant increase in glutathione levels and selective improvements in adaptive behavior and socialization domains ( Glutathione is able to improve the antioxidative system decreasing the oxidative damage and the neuroinflammation caused to the neurons (Ghanizadeh et al., 2012)