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In hypertensive children with normal renal function, there is a strong correlation between hyperuricemia and blood pressure (16), and in a controlled trial, treatment of these subjects with the xanthine oxidase inhibitor allopurinol significantly lowered blood pressure in a short-term study (17)

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doi: 10.1038/s41392-024-02095-6 68 CaoSSKaufmanRJ

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimers disease neurons