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Some of the richest natural sources include avocados, spinach, and asparagus

Interestingly, both in vivo and in vitro studies have shown that the accumulation of -syn in the mitochondria of human DA neurons leads to decreased complex I activity, increased production of ROS, reduced substrate-specific respiration, and increased mitophagy [86, 87]

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Though mitochondria were traditionally considered important cellular organelles due to their role in ATP generation, it is now evident that they play important roles in various cell signaling scenarios, including cell death by regulated necrosis [27]
This assessment was conducted using a polynomial quadratic model, which demonstrated an adequate precision of 11.2 and a reasonable disparity between the predicted R 2 (0.7078) and the adjusted R 2 (0.6387), with the difference being less than 0.2
