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For instance, aprotinin is a well-known serine protease inhibitor that has been co-formulated with insulin in thiolated chitosan xerogels, leading to a 70% reduction in enzymatic degradation and a 1.7-fold increase in insulin permeability across human EpiOral models and ex vivo sheep buccal mucosa [101]
What they did: Two parallel series of experiments
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This method allows the nutrient to enter the bloodstream directly through the small blood vessels in the mouth
