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Combinatorial therapy with deferiprone and N-acetylcysteine, exerted greater neuroprotection from iron-induced toxicity than monotherapy, including restored dendritic spine density, mitochondrial balance and ameliorated AD pathology (Sripetchwandee et al., 2014, 2016)

3D-printed scaffolds seeded with mesenchymal stem cells support cartilage regeneration, restoring cartilage thickness (49)

Dysregulation of these pathways contributes to impaired insulin secretion, altered lipid homeostasis, hyperglycemia, and metabolic dysfunction observed in obesity and type 2 diabetes [1]
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