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10.1016/j.ccr.2014.04.005 [DOI] [PMC free article] [PubMed] [Google Scholar] Paiva S

Pashneh-Tala, S., MacNeil, S

Singapore Med J

70 The endothelial dysfunction and the inflammatory state associated with infections drive patients towards a hypercoagulable condition, that translates into an increased thromboembolic and cardiovascular risk

Since aging is a primary risk factor in neurodegenerative diseases, it is likely that the age-dependent reduction in microbial species diversity, including alterations in relative abundances of region-specific microbes, further facilitates persistent degradation and damage of gut mucosal and gut epithelial layers and increases infiltrations of bacterial toxins (Qin et al., 2007