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However, treatment with DMSO was shown to improve functional recovery of cognitive function in rats after TBI through the enhancement of the bodys antioxidant defense system where it suppressed lipid peroxidation and reduces oxidative stress, and neuropathology

Gao N, Jiang B-H, Leonard SS, Corum L, Zhang Z, Roberts JR, Antonini J, Zheng JZ, Flynn DC, Castranova V (2002) p38 Signaling-mediated hypoxia-inducible factor 1 and vascular endothelial growth factor induction by Cr (VI) in DU145 human prostate carcinoma cells

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50 The use of free radical scavengers is an intriguing strategy for reducing TBI-induced oxidative stress Fig

This occurs through oxidation, reduction and hydrolysis of substances via cytochrome P450 enzymes