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The integrity of your gut barrier, oxidative damage from free radicals, toxic load, and inflammation all play a role

Cancer Res 66 , 91719177 (2006)

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Oral magnesium treatment exerts hypoglycaemic effects and potentiates the glutathione antioxidant system in alloxan-induced diabetic rats

This suggests a potential synergistic effect of Se and vitamin D in improving cognitive function, whereby Se may positively influence cognition by modulating vitamin D levels (318)
