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Pediatrics 2001;108(3):776-789

In traumatic injuries (neurotrauma, neuroinfection, stroke or immune attack), irreversible proliferative astrogliosis is essential for wound closure and formation of a glial border that separates fibrotic scar tissue from the healthy neural tissue and promotes postlesional regeneration

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While testosterone primarily increases muscle protein synthesis and reduces fat through androgen receptor activation, GH promotes lipolysis and collagen synthesis through separate pathways (Gibney et al., 2005)