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Moreover, NOX-4 is upregulated in lungs of mice treated with bleomycin and humans with IPF [24]
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This inflammatory reaction elicits resorbtion and the formation of fibrous connective tissue about the foreign body, causing dermal fibroplasia that leads to the desired cosmetic effect
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Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis
