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[DOI] [PMC free article] [PubMed] [Google Scholar] 604

[DOI] [PubMed] [Google Scholar] 163.Niculescu M.D., Craciunescu C.N., Zeisel S.H

As ALS progresses, microglia transition from protective M2 to neurotoxic M1 phenotypes, altering their influence on disease course (365)

The first two groups took 30 mg of lycopene daily, and the control group maintained a regular diet for three weeks

In this regard, as the circadian system is plastic and modifiable, chronomodulation, the strategic alignment of behaviors, treatments, and molecular interventions with the bodys internal clock, offers a compelling and multifaceted strategy to counteract the circadian system decay
