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Description
Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase-linked familial amyotrophic lateral sclerosis

Examples include superoxide dismutase (SOD), catalase, and GSH peroxidases (GSH-Px) a family of cytosolic, mitochondrial, and extracellular enzymes that detoxify lipid hydroperoxides and H 2 O 2 by oxidizing GSH to GSSG

In those cells incubated with BSO, CMFDA staining was similar or even higher than in control

the sulfhydryl is the most important functional group of GSH, can participate in various important biochemical reactions of organisms, protects important enzyme protein sulfhydryl in vivo from oxidation and inactivation, and ensures energy metabolism and cell utilization

Signs of degradation include complete lack of subjective or metabolic effects despite consistent dosing, or unusually severe injection site reactions