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Intriguingly, SP and L-car significantly reduced FOXO1 expression in the POI rat model, together with P53 and caspase-3 downregulation

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doi:10.1002/fsn3.2307

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UV exposure also produces NO and promotes melanin synthesis

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Besides improving fat metabolism, lipotropics will also aid in the metabolism of fat soluble nutrients and aid the liver in its other metabolic functions such as the processing of hormones, estrogen, sulfa-drugs, glucose and glycogen

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GDC-0994, FR180204, JNK-IN-8, and SP600125 were purchased from MedChem Express (NJ, USA)

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