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Arvela, Graham A

In animal studies it has lowered white adipose tissue mass and body weight while improving metabolic markers, typically without major changes in food intake
Examples of non-hydrogen substituents includes halogen, C1-4 alkyl, halogen-substituted C1-4 alkyl, NR 9 R 10 , NR 11 R 12 , and CN

Figure 1 NNMT is also involved in regulating autophagy to maintain cancer cell survival via the mTOR and AMPK pathways
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