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miR-375-3p can simultaneously downregulate FTH1 and FSP1 expression, jointly promoting ferroptosis (127)

While comorbid conditions like long COVID, fibromyalgia (FM), and postural orthostatic tachycardia syndrome (POTS) are common in ME/CFS, the more critical diagnostic complication arises from symptom presentations that resemble pre-malignant states, and undiagnosed rheumatic diseases, neurological diseases and endocrinopathies, increasing the risk of misdiagnosis

Precision medicine addresses this limitation by integrating diverse data sources such as electronic health records (EHR), medical imaging, and genomic sequencing, enabling a more comprehensive understanding of patient conditions and the formulation of tailored medical strategies

The authors could not provide data on the mechanism by which zinc affects vitamin E metabolism and/or function but hypothesized that zinc may affect the bioavailability of vitamin E: the deficiency of zinc may cause oxidative stress and depletion of the available vitamin E because it is oxidized in the process of combating peroxyl radicals
Supports the immune system, DNA maintenance, and wound-healing processes