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Epigenetic regulation of cytochrome P450 enzymes and clinical implication

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2019;298 doi: 10.1016/j.foodchem.2019.125044

lvarez-Avelln SM, Fernndez-Somoano A, Navarrete-Muoz EM, Vioque J, Tardn A

This resistance highlights the potential of combining SSP inhibition with dietary serine depletion to improve therapeutic outcomes, as demonstrated by recent work showing synergy between PSAT1 deletion and serine restriction in suppressing MYC-driven liver cancer [32]
