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These rats were then administered CAPE therapy at 10 mg/kg via intraperitoneal injection, commencing 30 min after the injury
Additionally, they observed extensive degeneration of dopaminergic neurons and associated behavioral deficits in microglia-specific Cav1.2 knockdown mice treated with MPTP, a neurotoxin-inducing PD-like symptoms
Mol Oncol (2021) 15(12):357895
Zhang W, Gong C, Chen Z, Li M, Li Y, Gao J
Of course, novel therapeutic strategies based on ROS mechanisms are not limited to antioxidant strategies
