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Description
Molecular and functional organization of adipose tissue AT plays an essential role in metabolic regulation beyond simple energy storage (22)
The ATP-binding Cassette (ABC) The ABC is the largest protein transporter superfamily present in all organisms
Arginine metabolic regulators such as spermidine have been shown to suppress M1 macrophage-associated cytokines while inducing M2 macrophage-related markers, significantly alleviating EAE symptoms, whereas Arg1 inhibitors can reverse these effects ( In other autoimmune diseases, amino acid metabolic reprogramming likewise participates in the formation of the inflammatory microenvironment by regulating macrophage polarization
The precise mechanisms of action and individual contributions of these components are unclear
Wadsworth, A
