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Their additive effects are evident in polygenic risk models, with PNPLA3 being the major contributor [279]

As a result, researchers can evaluate with a more complete research model rather than focusing on a single pathway
Silimarin also modulates various signaling pathways, including the NFB pathway, further contributing to its antiinflammatory and antioxidant effects

Harrison PM, Keays R, Bray GP, Alexander GJ, Williams R
Megherbi R, Kiorpelidou E, Foster B, Rowe C, Naisbitt DJ, Goldring CE, et al
