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Description
A phase I, randomized, SAD, MAD, and PK study of Risvodetinib in older adults and Parkinsons disease
L., Lisowski, K
The FDA last week issued warning letters against a handful of companies flagging violations regarding the promotion and sale of unapproved weight-loss drugs, including unlicensed versions of the blockbuster therapies semaglutide and tirzepatide
Recently a novel covalent inhibitor EN25 and its derivatives targeting GCLM subunit were discovered through covalent library screening, with a reported IC 50 of 16 M in 15 min reaction for EN25 and 6.8 M for the most potent derivative EN258 [71]
It comprises residues 17-23 and retains the actin-binding motif of the parent peptide
