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Exogenous GHRH administration enhances slow-wave sleep and GH release, improving subjective sleep quality (Born et al., Neuroscience Letters )

Phosphorylation of a GPCR increases its affinity to bind arrestin molecules eta-arrestins ( -ARrs) such as -ARr2, which are adaptor proteins that stabilize the GPCR in its uncoupled state and mediate its internalization

doi: 10.2337/diacare.28.5.1092

HO-1 inhibitors, including zinc protoporphyrin and more soluble pegylated derivatives (PEG-ZnPP), have been successfully used to improve chemosensitization of cancer cells [113]

[PubMed: 27531933] 213
