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Much of the housing stock built before 1978 contains paint that contains lead

New Phytol 185 : 577-588 (read) Lanoue A, Burlat V, Schurr U, Rose US (2010) Induced root-secreted phenolic compounds as a belowground plant defense
However, factors like aging, stress, and poor diet can lower glutathione levels over time
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This leads to the dissociation of TIMELESS from the replisome, slowing replication and resulting in replication stress and genome instability 17
