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Such effects may contribute to BC etiopathology 275

It can accumulate in the brain and adrenal glands (10 mM), where there are the highest concentrations of VIC, while in the muscle and myocardium, concentrations are lower (0.2 mM)

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However, limited long-term studies have shown supplement safety or effectiveness, so you may or may not experience any symptom relief when taking a supplement

Stadtman ER, Smyrniotis PZ, Davis JN, Wittenberger ME: Enzymic procedures for determining the average state of adenylylation of Escherichia coli glutamine synthetase