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2 Najran Health Cluster, Najran, Saudi Arabia

Mesenchymal stem cells (MSCs) are able to differentiate into skeletal and chondrogenic tissues, and also in neurons and glial cells [12,13]

The activated receptor phosphorylates insulin receptor substrate-2 (IRS-2), which in-turn activates the RAS activating protein SOS

NeuroSci 5:7186

Moreover, cancer cells carrying mutations of succinate dehydrogenase, fumarate hydrolase or isocitrate dehydrogenase accumulate -KG competitors including succinate, fumarate and 2-hydroxyglutarate, respectively 43,49,50
