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It was hoped that the drug would offer improved weight loss for patients with diabetes, who typically have a tougher time shedding pounds on existing GLP-1 treatments, but the 15.7% weight reduction result from the REDEFINE-2 trial disappointed

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Without extra vitamin B12, the combination of pernicious anemia and menstruation could be dangerous and have long-term consequences

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Mild irritation: redness, dryness, or itching at the application site