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all point out an increase in plasma enzymatic activity in more than 50% of patients after the dietary intervention, although no explanatory hypothesis has been yet suggested [83,85,86,123]

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Advanced maternal age in IVF: still a challenge

Finally, while sulforaphane is generally well-tolerated at low dose, clinical trials as higher sulforaphane doses can have unwanted side effects, such as lethargy, hypothermia, and gastrointestinal distress, although these generally occur at very high doses (Yagishita et al., 2019)