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After 24 h, the biofilm was washed once with 1 PBS and imaged using phase contrast microscopy (Zeiss, Axio, Germany), for bacterial adhesion and colonization

The varied success of anti-inflammatory agents suggests that targeting specific inflammatory pathways (like IL-1 or IL-6) or using agents with broad but relevant mechanisms (like colchicine affecting inflammasomes and neutrophil function) may be more effective than general immunosuppression (methotrexate) or targeting single enzymes (darapladib)
[PubMed] [Google Scholar] 157.Persson E., Henriksson J., Tallkvist J., Rouleau C., Tjlve H

10.1016/j.intimp.2025.114841 110 LiW.LiuY.WeiM.YangZ.LiZ.GuoZ.et al (2025c)
