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Huggins, C., Stevens, R

Acta Neurol Scand 101(3):209211 Di Prospero NA, Baker A, Jeffries N, Fischbeck KH (2007) Neurological effects of high-dose idebenone in patients with Friedreichs ataxia: a randomised, placebo-controlled trial

Together, these data place carnitine downstream of KG and demonstrate the necessity of the KGDD TMLHE and the de novo carnitine-synthesis pathway for resistance to DNA-damaging agents in HR-proficient models (Fig

Treat TMAO as a risk signal, not a standalone diagnosisinterpret it alongside renal markers, diet pattern, and related metabolites (e.g., choline, carnitine, betaine)