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Edward Dennis and co-workers developed some of the first large-scale oxylipin metabolic profiling methods in 2007, reporting the analysis of 60 eicosanoids in 16 min

Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids
Several clinical trials have demonstrated the efficacy of amantadine in reducing motor fluctuations in PD patients treated with levodopa [41]

Compared with the wild-type enzyme, Alda-1 demonstrates superior ability to activate dehydrogenase activity of the ALDH2 2*2 variant, an inactive mutated form of ALDH2 found in ~40% of the East Asian population (133)
