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Description
This set of enzymes is located in the ER and the main player is the ethanol-inducible cytochrome P450 2E1 (CYP2E1), which converts ethanol to acetaldehyde, generating ROS [140,141]
10.1038/s41467-023-37287-1
This is because the scarred tissue cannot move in response to muscle movements
2 AbiodunO

doi: 10.3389/fphar.2017.00319