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Trends Immunol (2022) 43(4):30921

Narrative evidence for COVID-19 consists of isolated case reports and mechanistic rationale

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The factors that integrate the pathways of ascorbate and GSH synthesis, recycling, and degradation remain poorly understood, although the compartmentation of these different processes is likely to be an important control point

The result of the loss of water (and overall volume) leads to the activation of the thirst mechanism ( polydipsia )
