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During the posterior embryonic axial development in mice and chicks, a glycolytic gradient is observed, which modulates the expression of various signaling pathways, thereby regulating developmental processes [176]

These diseases include COPD, asthma, interstitial lung disease, pulmonary sarcoidosis, and pneumoconiosis, such as silicosis and asbestosis (Vilcins et al

The emergence of new technologies like spatial transcriptomics and spatial metabolomics offers hope for identifying more potential metabolites in animal models, although effectively applying these methods to human samples remains a significant challenge

(PubMed) Hemila H, Chalker E