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The inactivation of NADH dehydrogenase I ( nuoI ) and NADH dehydrogenase II ( ndh ) reduces oxidized NAD (NAD + ), proton motive force (PMF), and positively charged aminoglycosides are difficult to enter cells, thus inhibiting the killing effect of aminoglycosides on bacteria, that is, improving the persistence capacity of bacteria

Nevertheless, the glutathione used is not lost, because a special enzyme the selenium-containing glutathione reductase converts the GSSG back into two active glutathione molecules

I discuss how dysfunctional tissue-specific metabolism during viral infections is likely to impact systemic metabolic homeostasis and long-term diseases, and how metabolic markers are being explored for prognostic purposes

When proteins are situated in an aqueous environment, in the absence of a salt, a dense layer of water molecules surround the protein which shield the hydrophobic patches