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For example, the mechanosensitive ion channel Piezo1 is markedly upregulated in the colonic mucosa of patients with UC (Zhou et al., 2025a), and its excessive activation exacerbates epithelial injury, in part by promoting ferroptosis (He H
doi: 10.1016/B978-0-12-418700-9.00009-5
L.JiangN.ZhaoJ
J Immunol (Baltimore Md: 1950) (2004) 173:35649
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