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Evidence also suggests that substrate channeling occurs between a metabolic unit (termed branched-chain amino acid metabolon) consisting of human BCAT m and BCKADHC and that the channeling is influenced by the redox state in mitochondria (Islam et al., 2007, Islam et al., 2010)
Glutathione levels naturally decline with age, chronic stress, poor nutrition, environmental toxin exposure, excessive alcohol consumption, and chronic illness
The clinical pathological data are summarized in Supplementary Table 1
Goldstein, A.L., Hannappel, E
