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Ubiquitination enzymes participate in lipid metabolism and contribute to the development and progression of various types of tumors ( Table 1 )

The rate-limiting step in this process is the carnitine shuttle, specifically the CPT-I enzyme that attaches carnitine to long-chain fatty acids so they can cross the inner mitochondrial membrane

In patients with HCV infection, it has been demonstrated that the HCV core antigen level strongly correlates with the HCV RNA level for various genotypes[62]

Gene set enrichment analysis Gene set enrichment analysis was performed using the WormCat 38

Here we review the evidence that cross-linking of sphingolipids may result in clustering of phosphatidylserine and transfer of signals to the cytosol