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Acetylcarnitine also induces antinociception through central cholinergic mechanisms involving M1 muscarinic receptors [106]

MATERIALS AND METHODS L-Lysine hydrochloride (Merck, Germany), L-carnitine-L-tartrate (KHF Chemicals, China), potassium dihydrogen phosphate (RDH, Germany), triethylamine (Merck, Germany), acetonitrile (Sigma Aldrich, USA), methanol (Sigma Aldrich, USA) and HPLC grade water was prepared in house using Milli-Q system (Millipore, MA, USA)