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3 The current standard regimen for drugsensitive TB involves a combination of drugs, including isoniazid (INH), rifampicin (RIF), pyrazinamide (PZA), and ethambutol (EMB)

Further study on the tumor tissue showed that the expression of Ki67 and p-c-Met were all reduced by all treatments, but, again, 1D228 stands out in overwhelming inhibition on cell proliferation and c-Met inhibition (Fig

The resulting suboptimal homeostasis of GSH results in a decreased capacity to minimize oxidative stress, which is associated with poor outcomes during ageing and in multiple disease states

The relationships between ferroptosis and antioxidants reveal significant perspectives in the management of this pathway for treatment