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The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)

doi: 10.1002/mc.22745

In Michigan in 2023, annual poison center exposures, emergency department visits, and emergency medical service responses related to nitrous oxide misuse were four to five times more than those seen in 2019 (264)

Step 7: Refrigerate and label Place the reconstituted retatrutide immediately in the refrigerator (2 to 8 degrees Celsius)