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At 6 months, the rate of decline in ALSFRS-R was less than what had been measured in a 3-month lead in period, though this was not statistically significant [163]

Future expression studies could analyse all isoforms of a particular enzyme in the cerebellum and compare a larger number of genes in different brain regions to clarify this observation

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Worth mentioning, the combination of SE with AST and PHA exerted pronounced hampering in ER stress markers and apoptotic markers, compared to any other group in this study