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Its main job is to neutralize free radicals unstable molecules that cause cellular damage known as oxidative stress

In addition, given the inherent day-to-day variability in function in the frail target population as well as the presence of a host of concomitant conditions, the appropriate patient population to be studied remains to be defined, and demonstration of clinically meaningful efficacy may be difficult

Furthermore, understanding the specificity of cellcell interactions across different brain regions is essential for explaining region-specific pathological changes observed in PD

The effect of L-dopa on the concentrations of tryptophan, tyrosine and serotonin in rat brain

Notably, exposure to nicotine-free e-vapor induces significant metabolic alterations and liver injury in dams and progeny, whereas nicotine-containing e-vapor promotes hepatic steatosis in adult offspring [135]