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The current vaccine against TB consists of attenuated Mycobacterium bovis strain, Bacillus Calmette-Guerin (BCG), which is almost 100 years old with variable efficacy, and is not effective in the adult population (Sepulveda et al., 1992

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It activates the powerful antioxidant pathway

They act as mighty messengers, sending signals to cells and tissues to perform a full spectrum of essential biological functions

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