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Moreover, the potential of personalized medicine in managing oxidative stress-related neurodegeneration is gaining momentum: genetic variants in the Nrf2 signaling pathway or SIRT1-mediated deacetylation affecting astrocytic GSH synthesis (e.g., regulating glutamate cysteine ligase catalytic subunit expression), combined with biomarkers like individual GSH levels and Nrf2 activity, could enable tailored interventions

10.1002/adma.202206286 51 NiuB.LiaoK.ZhouY.WenT.QuanG.PanX.et al (2021)

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A lower-dose aloe vera sterol-containing gel powder (19 g/d), increased skin barrier function and hydration in healthy adult females [77]

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