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485 AD risk is also increased by certain genetic predispositions, including at least 29 multigene loci, 486 and both genetic and nongenetic factors contribute to the estimated 6080% heritability of AD

Newton TF, De La Garza R Jr, Kalechstein AD, Tziortzis D, Jacobsen CA (2009) Theories of addiction: methamphetamine users' explanations for continuing drug use and relapse
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