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Results Establishment of CRC Drug-Tolerant Persister Cell Models While modeling the response to the chemotherapeutic drug 5-FU in the CRC cell line HCT116, which has exquisite sensitivity, we observed that the vast majority of the cells were killed within 9 days of exposure to the drug at a concentration 10-fold higher than the IC 50 value ( Figure 1A )

[8] Disclaimer: This compounded medication is prepared under section 503A of the U.S

Phytomedicine 118 , 154962 (2023)

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Conclusion From Molecule to Market Leader The product journey of an API is a testament to precision, innovation, and compliance