intracellular antioxidant glutathione The Biological Functions of Cellular Compartmentalization, Glutathione Transport and
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Persistent IL-2 stimulation in CD8 + T cells leads to chronic activation of STAT5, which leads to the expression of tryptophan hydroxylase 1 [201]

Citation: Phillips, A., & Clements, J

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria
The three forms of vitamin B12, cyanocobalamin, methylcobalamin, and adenosylcobalamin have been shown to have different conversion and absorption rates, with methylcobalamin (the naturally occurring form of B12) regarded as the most optimal for assisting in the methylation cycle

Nevertheless, the pathogenetic mechanism of type 1 AIP still remains unclear