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Therefore, targeting the KRAS-NRF2-glutaminolysis axis holds significant potential for buffering mitochondrial ROS and overcoming chemoresistance to improve outcomes in KRAS-driven cancers
[DOI] [PubMed] [Google Scholar] 147.Maheshwari R.K., Singh A.K., Gaddipati J., Srimal R.C
Hutter C
The recent elucidation of receptor-mediated (LDLR) actions of MT-1/2 makes it difficult to discriminate between receptor mediated actions of MT-1/2 and those arising from its action as a modulator of zinc intracellular levels or as a potent scavenger of ROS
J Biol Chem 287(24):2014420153
