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Virmani A, Pinto L, Bauermann O, et al

10 Although there is more limited information about the use of supplements to treat neuropathic pain compared to first-line agents, alpha-lipoic acid (ALA), also known as thioctic acid, and acetyl-L-carnitine (ALC) have shown to be efficacious forms of treatment for diabetic neuropathy with less adverse side effects when compared to the traditional first-line treatment options

ALCAR/ALA treatment significantly reduced phosphocreatine levels in the parieto-occipital cortex at week 12 ( P = 0.002)

Central nervous system and peripheral hormone responses to a meal in children

3,4 The first study showed that adding PEA reduced the number of painful areas and decreased pain scores by 25%
